The primary aim is to facilitate an overall well-being for patients suffering from incurable neurological disorders through Neuroregenerative Rehabilitative Therapy (NRRT). In addition to the above, providing support to cellular therapy research & regenerative medicine and increasing awareness about its applications are supplementary objectives.

Some time ago donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.

Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.

Stem cells, from different sources, have three common properties: The stem cells do not have tissue-specific structures to perform specialized functions.

Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.

For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.

These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.

How do the infused stem cells act? Once infused into the body,

– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.

Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read more details at NeuroGen BSI.

Many specialists recommend starting physical therapy as early as possible to prevent future complications like contractures-a shortening of muscles and tendons that can be painful and is common in spastic cerebral palsy. Strength training exercises are also helpful for children with dyskinetic cerebral palsy who have loose muscles and may experience atrophy. Occupational therapy helps children with cerebral palsy improve fine motor skills. In general, physical therapy is used to improve gross motor function, but it doesn’t focus on fine motor function. People with cerebral palsy struggle with coordinating these skills for tasks such as grasping a spoon and bringing it to their mouth. But occupational therapists often work with physical and speech therapists to build a complete therapy plan.

A few advices to help your child with autism: Stick to a schedule. Children with ASD tend to do best when they have a highly-structured schedule or routine. Again, this goes back to the consistency they both need and crave. Set up a schedule for your child, with regular times for meals, therapy, school, and bedtime. Try to keep disruptions to this routine to a minimum. If there is an unavoidable schedule change, prepare your child for it in advance. Reward good behavior. Positive reinforcement can go a long way with children with ASD, so make an effort to “catch them doing something good.” Praise them when they act appropriately or learn a new skill, being very specific about what behavior they’re being praised for. Also look for other ways to reward them for good behavior, such as giving them a sticker or letting them play with a favorite toy.

Supports and repairs cells: Everything we do is based on our cells. The way we act is affected by cellular health. Cellular problems create latency; By feeding them well, they can become much more energetic and efficient. Relax! Remember the last time you spent a whole day in a crowded shop or amusement park. You were probably exhausted when you got home. The brain of people with autism can feel that chaos and exhaustion all the time. By understanding how your child’s brain works and taking the right measures, you will make your and your child’s world easier to manage. Enter the world of your child! Look for the hidden reasons for the child’s behaviors. Odd or provocative behaviors are usually a sign that something is not perceived correctly.

Did you know that the first successful stem cell transplant took place in 1988? That year, doctors used the blood sample from the umbilical cord of a newborn to treat Fanconi’s syndrome, which his 5-year-old brother suffered from. It is estimated that more than 22,000 stem cell transplants from umbilical cord blood have been performed worldwide.

The spinal cord is the chief line of the nerve tissues that give rise to the spinal nerves. They connect the brain and the vertebral canal to the rest of the body. A spinal cord injury, disrupts this connection. Defects in the sensory, motor and reflex messages, are detected after a spinal cord injury. After such a trauma, a person may not be able to function properly and the condition could worsen when the level of injury is higher. A cervical spinal cord injury involves the loss of movement & function in all four limbs. Quadriplegia involves the arms, legs, hands and pelvis after a cervical spinal cord injury. The spinal cord injury symptoms associated with a cervical spinal cord injury are difficulty in respiration, loss of bladder & bowel movement, loss of limb function. Due to prolonged lackof movement, this type of spinal cord injury increases the chances of bedsores, or decubitus ulcers. Read extra details Stem Cell Treatment For Spinal Cord Injury.